scleroderma

Scleroderma sklair-oh-DUR-muh is a group of rare diseases that involve the hardening and tightening of the skin and connective tissues. A connective tissue disease is one that affects tissues such as skin tendons and cartilage.

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Scleroderma literally means hard skin.

. It happens when your immune system causes your body to make too much of the protein collagen. Some people develop violet-colored skin which means that the scleroderma is active and expanding. Among them is collagen of the skin.

Tissue culture and enzyme studies indicate increased fibroblastie activity and collagen production during the active state of scleroderma 5 6. The word scleroderma comes from the Greek word sclero meaning hard and the Latin word derma meaning skin. Scleroderma involves many systems in your body.

In patients with scleroderma the immune system triggers other cells to produce too much collagen a protein. However the relative proportions of Type I and Type III collagen appear similar to those of normal adult dermis 7. While there is no cure for scleroderma a variety of treatments can ease symptoms and improve quality of life.

Scleroderma probably is both a vascular disease and an autoimmune disorder 4. Calcinosis Raynauds phenomenon esophageal. Skin color changes The patches of hardened skin can be lighter or darker than your natural skin color.

Scleroderma or systemic sclerosis is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases. Scleroderma is a long-lasting disease that affects your skin connective tissue and internal organs. It adds strength to organs and other parts of the body Connective tissue is made of many kinds of proteins.

Connective tissue is widespread. Normally the immune system helps defend the body against disease and infection. Scleroderma is an autoimmune rheumatic and chronic disease that affects the body by hardening connective tissue.

Systemic sclerosis is also called scleroderma progressive systemic sclerosis or CREST syndrome. This inflammation leads to patches of tight hard skin. Scleroderma affects women more often than men and most commonly occurs between the ages of 30 and 50.

Scleroderma causes extremely dry skin and dry skin itches. The extreme dryness can cause the skin to breakdown and sores can form. Scleroderma is a group of autoimmune diseases that may result in changes to the skin blood vessels muscles and internal organs.

Scleroderma is a chronic although rare autoimmune disease in which normal tissue is replaced with dense thick fibrous tissue. Symptoms may include areas of thickened skin stiffness feeling tired and poor blood flow to the fingers or toes with cold exposure. Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body.

The disease can be either localized to the skin or involve other organs as well.

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